Zelle und Autophagie

Spermidine cleanses the cells
with autophagy

What is spermidine?​

Spermidine is a natural polyamine that occurs as a messenger substance in every cell of the body. It is a compound of amino acids and is closely linked to cell growth. One of its essential functions in cell metabolism is to “switch on” the cellular cleansing processes, known as autophagy.

Autophagy is a kind of recycling plant of human cells.

Autophagy is a kind of recycling plant of human cells. During this self-cleaning process, faulty or no longer required cell components are broken down, utilised and converted back into cell energy. Because autophagy loses efficiency with age, disease-related changes occur. Deposits in the cells, which in turn may lead to dementia, diabetes, tumors and atherosclerosis. The increased uptake of spermidine signals the cells to start these self-cleaning processes and thus protects against deposits and premature ageing.

Discover our products and support your cell health.
Because cells are the building blocks of life.

"Science & Natural Resources"

spermidineLIFE® was the first natural spermidine supplement on the market and 

remains the only spermidine product with Novel Food approval in Europe until today.

Natural spermidine
Natural spermidine
Clinically tested
Clinically tested
for cell renewal
For cell renewal
Entwickelt in Österreich
Developed in Austria

This approval ensures that the products meet the strict safety and quality standards of the EU.
The Novel Food approval is a complex process that requires a comprehensive safety assessment and compliance with specific regulations. spermidineLIFE® has successfully completed this process and is thus the only company worldwide to offer spermidine products with this certification. Researched and developed by Prof. Frank Madeo, who is considered the discoverer of spermidine, with Longevity Labs+, a spin-off of the University of Graz.

The products in the spermidineLIFE® line are 100 % natural and contain spermidine from wheat germ, as well as zinc, that’s protects the cells from oxidative stress.

Patented CelVio® Complex

The secret ingredient in all spermidineLIFE® products: the CelVio Complex®. This complex is used by scientifically recognized research teams worldwide in studies and is a top innovation in the field of cellular renewal.  


Due to the Novel Food authorisation and the 100% naturalness of CelVio Complex®, human research can be carried out with our spermidine-rich wheat germ extract.

Longevity Labs+ produces the spermidine extract in its own production facilities in Graz. In this way, the high quality and content of spermidine can be guaranteed. The natural phytoextract combines spermidine, vitamins, unsaturated fatty acids and other phytochemicals in the bioavailable CelVio® Complex.

Quality Comes First

The spermidine content of wheat germ can vary greatly. Therefore, in terms of both quality and sustainability, we rely on certified suppliers from Central Europe.

The wheat germs are GMO-free and undergo double testing for quality, purity, and especially spermidine content—once before and once after extraction. The extraction itself is carried out in-house at our production site in Graz, Austria. This is the only way to ensure effectiveness and a guaranteed spermidine content.

What makes our product so unique?

spermidineLIFE ist Weltmarktführer und das weltweit einzige offiziell zugelassene Spermidinpräparat (Novel Food in der EU). Die Zulassung von spermidineLIFE hat die Humanforschung erst ermöglicht. Bis dato wurde es in 8 klinischen Studien eingesetzt. spermidineLIFE® is extracted from natural wheat germ sourced from Central Europe and produced in Graz using a specially developed extraction process. Due to its approval, there are safety and tolerability studies, which are essential for therapeutic intervention. Other spermidine supplements often do not guarantee quality and spermidine concentration. They are mostly derived from soy (methionine in soy can inhibit cell renewal) or enriched with synthetic spermidine (e.g., buckwheat – which contains hardly any spermidine itself). The natural CelVio® Complex in spermidineLIFE® is unique. In addition to spermidine, it contains other polyamines (spermine, putrescine), healthy fats, vitamins, and minerals.

Science is passion

Our life expectancy has increased steadily in recent decades. In order to experience a long life span in a healthy way, the cell scientists scene is intensively concerned with cell aging and cell renewal.

Renowned scientist Yoshinori Oshumi won the 2016 Nobel Prize for research into the autophagy process, laying the foundation for the spermidine innovation.

Spermidine at the center of cell research

The polyamine spermidine has been at the center of cell research since the discovery of autophagy in 2016. The polyamine spermidine has been at the center of cell research since the discovery of autophagy in 2016. A whopping 13’440 studies have been conducted on spermidine, showing the immense potential of spermidine.
The research department of SpermidineLife is based at the University of Graz, Austria. The Institute for Molecular Biosciences with the laboratory Frank Madeo and Tobias Eisenberg is in charge of research into the top molecule spermidine.

Spermidine Research Report

Due to the revolutionary research results at the University of Graz, Austria, spermidine has gained a lot of attention worldwide in recent years.

Around 80 international research teams are currently researching the substance spermidine or autophagy. Despite the short period of investigation by scientific standards, there are few substances that have been better and more intensively researched than spermidine.

Spermidine, the scientific secret for a long healthy life

spermidineLIFE® Pro+

High-dose cure to start your spermidine intake

  • Highly dosed with 6 mg natural spermidine
  • Achieves quick results
  • Ideal for starting spermidine intake as an interval cure 3–4x per year

Studies have shown that spermidineLIFE®-products show the full potential of their positive effects, especially with regular and long-term use. Whereby it makes sense to start the cell cleansing & cell renewal with higher doses at the beginning of the intake.

Recommended intake:

1 sachet daily dissolved in water
Box with 30 sachets for a monthly cure

Start your spermidine intake with the high-dose spermidineLIFE® Pro+,  to start autophagy.

spermidineLIFE® Boost+

The Energy boost for stressed cells

  • Maintenance dose in sachets

  • With 3 mg of natural spermidine per daily dose

  • Intervals recommended in combination with spermidineLIFE® Pro+, 3–4x per year.

In stressful phases of life or with increasing age, the body often needs more support. This is why spermidineLIFE® Boost+ contains a higher amount of spermidine at 3 mg per daily dose.

spermidineLIFE® Boost+ supplies the cells with 3mg of natural spermidine, as well as zinc and thiamine.

Recommended intake:

Take 2 capsules daily

The extra boost of cell renewal for every day.

spermidineLIFE® 365+

The foundation for 365 days of cell health

  • Maintenance dose in sachets
  • With 2 mg of natural spermidine per daily dose
  • Intervals in combination with spermidineLIFE® Pro+ recommended 3–4x per year
The spermidineLIFE® Original 365+ capsules are suitable as a maintenance dose for daily intake. Interval treatments with spermidineLIFE® Pro+ are recommended 3-4 times a year.

Recommended intake:
Take 2 capsules daily

nadLIFE® Energy+

Energy for Your Cells

  • An innovative combination of NAM – a form of niacin, ribose, spermidine and zinc
  • Provides the cells with new energy
  • Suitable as a combination treatment with spermidineLIFE® Boost+ or spermidineLIFE® Original 365+

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme that occurs in all living cells. It acts as an electron carrier in the mitochondria and is therefore crucial for ATP production (Adenosine Triphosphate, ATP). ATP is an energy-rich compound that occurs in all living cells and serves as a universal energy carrier. It supplies the energy for numerous processes in the cells. Unlike other NAD+ supplements that do not use NMN as a source of niacin, NAM passes directly through the cell membrane and does not need to be transformed. Through this efficient process, you support your cells‘ energy balance even better and give your body more vitality.

Recommended intake:
Dissolve the contents of one stick in a glass of water once a day and enjoy

Not all capsules are created equal!

With so many dietary supplements on the market, it’s easy to lose track of all the different product properties. We show you the most important differences between spermidineLIFE® and other spermidine products. Trust the world market leader!

SpermidineLife 365. Das Original, Pro.

spermidineLIFE


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