What is the effect of spermidine?
Spermidine acts as a fasting mimetic that activates autophagy.
Autophagy
The process at the core of cell renewal
What is autophagy?
Autophagy (“self-eating” in Greek) is a critical process in cellular function and regeneration. It is a cellular recycling process in which cells metabolize damaged components and produce energy as a result.
Damaged cell components contribute significantly to the development of age-related diseases. Through the activation of autophagy, cells are kept “young” and healthy. Autophagy is essential for normal cell function.
The process was elucidated by Yoshinori Ohsumi, who received a Nobel Prize in 2016.
Autophagy can be induced by fasting (caloric restriction), exercise, and some supplements, such as spermidine.
Since cells are the fundamental units of every organ system, stimulating their autophagy process could be a powerful strategy for combatting the mental and physical signs of aging.
Fasting made functional
Experience the power of the Celvio Complex
Embracing and maintaining regular fasting to activate autophagy and gain its health benefits can be challenging for many people. Additionally, fasting may not be recommended for certain groups of people, such as:
- People of advanced age
- People with cardiovascular problems
- People with low weight
Spermidine helps activate the process of autophagy without having to rely on fasting.
What is the link to fasting?
Fasting and caloric restriction is the most natural way to activate autophagy. The lack of energy due to reduced food consumption means that our cells must resort to internal alternative energy sources, such as damaged cell components. These defective components are metabolized in the cell, and new energy is produced.
Any form of avoidance or reduction of caloric ingestion, such as fasting, activates autophagy and thus contributes to an improvement in cellular health. However, this requires a high degree of discipline, as it is usually difficult to integrate fasting as a daily routine.
We know that fasting extends the healthspan and lifespan of organisms by boosting autophagy through an increase in spermidine production.
Spermidine supplementation can trigger the benefits of fasting without having to strictly fast.
A recent study published by our research partners and their collaborators found that fasting increases the production of spermidine, a key molecule that activates autophagy. Autophagy, in turn, plays a crucial role in maintaining cellular health and preventing age-related diseases. By working together, fasting and spermidine can significantly enhance the benefits of autophagy. Supplementing with spermidine during fasting may maximize the health benefits of fasting.
Spermidine is key to unlocking the health benefits of fasting.
Without spermidine, cellular recycling is reduced, leading to fewer positive effects of fasting on overall health and lifespan.
Start your spermidine routine with the high-dose spermidineLIFE Pro+ to activate autophagy. Ideal to begin the spermidine supplementation or as a premium protocol for long-term use.
