Collagen Clinical studies. Scientifically confirmed effectiveness. Collagen peptides cause the body to produce more collagen.
Collagen Clinical studies. Scientifically confirmed effectiveness. Collagen peptides cause the body to produce more collagen.
Clinical studies Solugel®
Scientifically confirmed effectiveness
Collagen Clinical studies. Scientifically confirmed effectiveness. Collagen peptides cause the body to produce more collagen.
Why does it make sense to take HIGH COLLAGEN®?
Collagen is the most abundant protein in the human body
Collagen fibres are the central building blocks of connective tissue
They support and stabilise fibres and tissue.
Collagen can be found almost everywhere in our body:
in the skin, bones, muscles, fasciae and tendons, in cartilage and in all connective tissues.
Our body produces the necessary collagen itself, but collagen production slows down from the age of 20. This results in brittle nails and hair, dry skin and wrinkles, muscle loss, inflexible joints and limited mobility.
To counteract this, it makes sense to support the body with high-quality collagen!
Collagen Clinical studies. Scientifically confirmed effectiveness. Collagen peptides cause the body to produce more collagen.
Collagen provides structural support
for
the extracellular space of the connective tissue
Collagen is present throughout the structural elements in the body.
Collagen has a triple helix alpha chain composed of amino acids in its native structure
Collagen Clinical studies. Scientifically confirmed effectiveness. Collagen peptides cause the body to produce more collagen.
HIGH COLLAGEN® - Beauty & Skin Health
The crucial Role of Collagen for a healthy skin
The skin can be considered to be the largest organ of the human body and its appearance reflects both our health and overall wellbeing.
Skin aging has been extensively studied over the last decade. The visible effects of aging are the result of a sequence of events that begin with UV light exposure and result in collagen fragmentation as the final outcome.
Collagens are particularly important for the strength and resilience of the skin. To this end, changes in their number and structure are thought to be responsible for wrinkle formation, loss of skin smoothness, hydration and firmness.
SOLUGEL® clinical study beauty from within
A placebo-controlled double-blind study on women aged between 35 and 55 years was undertaken in order to investigate the positive effect of the oral intake of SOLUGEL® collagen peptides on skin mechanical properties both before and after a treatment period that lasted eight weeks.
A total of 54 women were selected according to strict inclusion criteria and their skin properties were closely monitored. The group was divided in two: one placebo group of 28 women, and a SOLUGEL® group of 26. During the study, either 0g or 10g of SOLUGEL® were ingested.
Better skin firmness and elasticity
The daily intake of SOLUGEL® collagen peptides led to improvements of the biomechanical properties of the skin. Following 56 days of treatment, the group with the SOLUGEL® intake demonstrated a better skin firmness, as well as elasticity compared to the placebo group
(see figure 1).
Significant improvements of skin hydration
The study showed that the daily oral intake of 10g SOLUGEL® significantly improved the skin hydration after 56 days. The results (which were measured by a Corneometer) demonstrated an increase in the moisture level of up to 14% (see figure 2).
In addition to measurements with a Corneometer, the visual effect of the Moisture Map is clear evidence of the improved skin hydration as a result of the daily SOLUGEL® intake.
Below is an example (see figure 3) of two pictures that were taken by the Moisture Map (hydration of the skin) from a volunteer who had the SOLUGEL® oral intake. There are far more darker spots on the D56 picture than the D0 picture, which indicates the increased moisture level over the treatment period. The results of the Corneometer confirmed the improved moisture level of this particular volunteer: The darker the picture, the more hydrated is the skin.
Clinically confirmed
Volunteers’ self-assessment
During the study, subjective questionnaires were answered by all of the volunteers in order to evaluate the cosmetic qualities and efficacy of the tested products. The group treated with the SOLUGEL® intake demonstrated a better perception of the product efficiency compared to the placebo group in terms of:
- Skin hydration
- Firmness of the skin
- Appearance of the skin
- Overall improvement of the skins texture and condition
This clinical study has proven the positive effects of oral intake of 10g SOLUGEL® collagen peptides on skin elasticity, firmness, as well as skin hydration after 56 days.
Collagen peptides cause the body
to produce more collagen
Human dermal fibroblast cultures (blue) after 24 hours of treatment. An increased collagen expression can be observed in the Solugel® group compared to the placebo control group.6
Further human clinical studies confirm that taking 5-10g of Solugel® collagen peptides for 4 to 12 weeks has positive effects on skin hydration, elasticity, wrinkles and suppleness.
HIGH COLLAGEN®- Physical activity & performance
New clinical evidence:
Effect of collagen peptides’ intake on function, pain, and mental well-being in active middle-aged adults
SOLUGEL® clinical trial
has novel findings
Previous research established
- Collagen can reduce joint pain among those suffering with conditions
- such as osteoarthritis, joint stability problems, injured joints, or exercise-induced issues
SOLUGEL® clinical trial established
- Collagen’s long-term impact on joint pain, daily living activities and mental well-being in the healthy and active middle-aged population is determined for the first time
Wissenschaftlich nachgewiesene Auswirkungen
auf die Gesundheit der Gelenke
Supplementation of SOLUGEL® collagen peptides supports the
continuation of the routine of daily physical activities
HIGH COLLAGEN® improves daily activities
Double-blind, randomized and placebo controlled human study
- Activities of Daily Living (ADLs) are the tasks basically related to the ability to carry out everyday tasks such as commuting, cleaning and shopping etc.
- The capability to remain independent of daily activities is crucial for active adults. The improvement of the ADLs score indicates better independence in daily activities.
- 10g/day SOLUGEL® intake for 6 months resulted in statistically significant improved ADLs scores compared to placebo group (*p<<0.05) while placebo group shows no improvements.
This novel study was carried out at Institute of Sports Sciences and Medicine, Florida State University
References:
1. Kviatkovsky, S.A., et al., Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults. J Int Soc Sports Nutr, 2023. 20(1): p. 690-707.
2. Kviatkovsky, S.A., et al., Peptide Supplementation Improves Measures of Activities of Daily Living and Pain in Active Adults. J Int Soc Sports Nutr,, 2022. 19 p. 35-36.
SOLUGEL® Collagen peptides Scientifically proven mental well being effects
Already after 3 months!
10g/day SOLUGEL® intake resulted in improved mental well being significantly!
References:
• Arthritis Foundation. Survey: Arthritis Pain Slows Exercise. https://www.arthritis.org/about-arthritis/types/osteoarthritis/articles/exercise arthritis pain slows exercise.php
• Innova Lifestyle & Attitudes Survey
References:
• Kviatkovsky, S.A., et al., Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults. J Int Soc Sports Nutr , 2023. 20(1): p. 690 707 – https://pubmed.ncbi.nlm.nih.gov/37551682/
HIGH COLLAGEN® - The natural solution
for strong bones & healthy joints
Osteoarthritis and joint metabolism
Osteoarthritis (OA) is a joint inflammation resulting from cartilage degeneration. Osteoarthritis can be hereditary, or caused by aging, or a traumatic injury. Of those with osteoarthritis, 80 % suffer limited movement and as much as 20 % cannot perform their daily activities.
A joint is the point where two or more bones are connected. In a healthy joint, the ends of the bones are encased in smooth cartilage to absorb the shock of movement and distribute the body’s load. Joints are composed of chondrocytes (2-10 %), living cells, and an extracellular matrix (ECM) maintained by the chondrocytes.
This matrix consists of fluid (80 %) and structural macromolecules like collagen (12 %), proteoglycans (5-7 %) and non-collagenous proteins (3-4 %).
Chondrocytes have a central role in the metabolic processes characterized by a slow, continuous turnover of the ECM to maintain healthy cartilage. Our joints undergo significant changes as we get older, practice sports or engage in day-to-day activities, all of which may affect cartilage turnover, ultimately leading to an imbalance between cartilage build-up and breakdown. This can lead to chronic joint symptoms such as discomfort, stiffness, loss of flexibility and even swelling.
There is no known cure for osteoarthritis, therefore the objective of most treatments is pain reduction, increasing joint mobility, and preventing or limiting further damage.
Evolution of osteoarthritis
- Bones
- Cartilage
- Thinned cartilage
- Cartilage fragment
- Destruction of cartilage
Scientifically proven
joint health effects
Supplementation of SOLUGEL® collagen peptides helps to reduce joint pain
HIGH COLLAGEN® reduces joint pain
Double-blind, randomized and placebo controlled human study
- Pain is a major limiter of physical activity and daily living activities for everyone, contributing to lower well-being and increased disease risks.
- Pain score evaluates the degree of joint pain and functionality of the knee in the movements experienced by the participants.
- 10g/day SOLUGEL intake for 6 months resulted in statistically significant reduced joint pain scores in more frequent exercisers compared to placebo group (*p<< 0.05 ). Furthermore, pain scores were worsened in placebo group. Furthermore, pain scores were worsened in placebo group.
HIGH COLLAGEN® & Weight Control
SOLUGEL® provides long-lasting satiety and delays hunger
Results showed that breakfasts containing SOLUGEL® caused a significant 20% lower energy intake at lunch compared to casein and soy breakfasts at both 10% and 25% protein concentrations. The reduced energy intake of 20% was related to a 40% reduction in appetite.
Scientifically proven effects
Scientific evidence proves that bioactive SOLUGEL® collagen peptides outperform other proteins
by providing long-lasting satiety and delaying hunger.
HIGH COLLAGEN® Shots is the ideal protein source to support your weight management diet.
SOLUGEL® collagen peptides offer numerous health benefits for skin, joints, and bones due to their bioactive properties. Collagen: Collagen is the most abundant protein in the human body, accounting for more than 30% of total body protein. It is present in all connective tissues such as skin, bones, cartilage, tendons, and blood vessels. SOLUGEL® Collagen Peptides: A highly digestible protein obtained through the enzymatic treatment of collagen-rich materials. Produced from high-quality raw materials using a unique biotechnological process. Differences Between Gelatin and Collagen Peptides: Gelatin is mainly used as a gelling agent, while collagen peptides are consumed primarily for their nutritional and physiological benefits. Health Benefits: Clinical studies show positive effects on skin, joints, bones, weight management, and sports performance. Effects on the Skin: Collagen peptides stimulate collagen synthesis and improve skin hydration and elasticity. A study showed that taking 10g of SOLUGEL® daily for 56 days significantly enhanced skin performance. Effects on Joints: Improves joint structure and may have anti-inflammatory effects. Effects on Bones: Supports bone metabolism and helps maintain bone density. Satiety Effects: SOLUGEL® can delay the feeling of hunger by increasing the insulin response and the release of specific molecules. Absorption in the Body: Collagen peptides are hydrolyzed into smaller peptides or amino acids in the digestive tract and reach the bloodstream within 15 minutes. Combination with Other Proteins: Thanks to its neutral taste, SOLUGEL® can be easily combined with other proteins such as whey. PDCAAS Value: Collagen peptides can be blended with other proteins to achieve a PDCAAS score of 1. Recommended Daily Intake: The recommended dosage ranges from 2.5 to 15g per day, depending on the desired health benefits. Amino Acid Profile: Contains 8 of the 9 essential amino acids and is rich in hydroxyproline, glycine, and proline. Production Process: Extraction is carried out through a strictly controlled enzymatic process that ensures a high-quality product. Raw Materials: Derived from bovine sources and therefore not suitable for vegetarians.
Bioactive Properties: SOLUGEL® collagen peptides are bioactive ingredients produced using advanced technology. Safety: As a natural ingredient, they are considered safe and free from allergenic substances. Type of Collagen: Consists of Type I and Type III collagen—the most common collagen types in the human body. Kosher and Halal: Kosher and halal certified versions are available. Grass-Fed and Pasture-Raised: Products made from pasture-raised and certified grass-fed sources are available.