In recent years, scientific research has shed light on various molecular mechanisms underlying aging and age-related diseases, offering promising avenues for intervention. One such emerging agent is spermidine, a naturally occurring polyamine found in all living cells. Spermidine has gained considerable attention due to its potential role in promoting cellular health and longevity through a process called autophagy. Spermidine has been shown to exhibit anti-inflammatory properties which may contribute to its protective effects against age-related diseases.

A Look at Recent Findings

Spermidine in Health and Disease

As we age, our body’s ability to keep up with the demands of everyday life starts to decline, leading to stress, disease and deterioration. Diseases that typically come along with aging include diabetes, cardiovascular disease, cancer and neurodegenerative diseases. In the research being conducted on how to combat these age-related pathologies and increase one’s longevity, fasting regimens and dietary adaptations like caloric restriction have surged to the front as being effective ways to increase healthspan and lifespan. Caloric restriction has many benefits, though…

Spermidine in the Spotlight

Dr. Elizabeth Yurth, Co-Founder and Chief Medical Officer of Boulder Longevity Institute, joins Dave Asprey to delve into the mechanisms of autophagy and its critical role in promoting longevity and preventing disease. Listen as these two explore the impacts of supplements like spermidine and discuss strategies for enhancing cellular health.

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What is spermidine?
What is spermidine? Our bodies naturally produce spermidine in nearly every cell of our body, though as the body ages, our spermidine levels decline. Our body’s cellular health declines as well as our natural cellular maintenance processes begin to slow down. People who experience chronic inflammation and low immunity may benefit from an increase in spermidine…
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Spermidine Supplementation and Its Effect on Hair Health
In a double-blind, randomized and placebo-controlled studies, 100 men and women were separated into two groups: a placebo group and a treatment group. Participants in the treatment group took an oral spermidine supplement after their main meal once a day. This study specifically looked at the anagen phase of the hair growth cycle…
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